Carpal tunnel syndrome (CTS) is a collection of characteristic 
symptoms and signs that occurs following entrapment of the median nerve 
within the carpal tunnel. Usual symptoms include numbness, paresthesias,
 and pain in the median nerve distribution. These symptoms may or may 
not be accompanied by objective changes in sensation and strength of 
median-innervated structures in the hand. See image below.
The
 hands of an 80-year-old woman with a several-year history of numbness 
and weakness are shown in this photo. Note severe thenar muscle 
(abductor pollicis brevis, opponens pollicis) wasting of the right hand,
 with preservation of hypothenar eminence
The
 hands of an 80-year-old woman with a several-year history of numbness 
and weakness are shown in this photo. Note severe thenar muscle 
(abductor pollicis brevis, opponens pollicis) wasting of the right hand,
 with preservation of hypothenar eminence
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